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Tier 3 · mechanistic / traditional / early human

Cyanidin-3-glucoside (black rice / bilberry, 25% C3G)

Anthocyanin RCTs (320 mg/day) improved HDL/LDL and endothelial markers; C3G-specific human data limited.

5/10evidence score
100 mgstudied dose used

What the evidence shows

Anthocyanin RCTs (320 mg/day) improved HDL/LDL and endothelial markers; C3G-specific human data limited.

Tier is our appraisal of the human evidence at the dose we use: Tier 1 = multiple randomized trials; Tier 2 = human trials, fewer or smaller; Tier 3 = mechanistic, traditional or early human data; Tier 4 = emerging. Ingredients below Tier 2 are included only where the safety record is long and the traditional use is specific.

Form and dose

Form used
Anthocyanin extract standardized to C3G
Dose per serving
100 mg
Delivery
Standard / as studied

Who should be careful

None significant. Talk with your clinician before starting if any of this applies to you.

In our formulas

FAQ

Which NEX-GEN formulas contain Cyanidin-3-glucoside (black rice / bilberry, 25% C3G)?

Ultimate Longevity (100 mg per serving). Every formula lists its full dose on the Supplement Facts panel — no proprietary blends.

What form of Cyanidin-3-glucoside does NEX-GEN use and why?

Anthocyanin extract standardized to C3G. We choose the most bioavailable form we can source at the studied dose.

What does the evidence actually show for Cyanidin-3-glucoside?

Anthocyanin RCTs (320 mg/day) improved HDL/LDL and endothelial markers; C3G-specific human data limited.

Who should be careful with it?

None significant. Talk with your clinician before starting if any of this applies to you.

Sources

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition. Last reviewed October 2026.

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