Skip to content
Version 2.0 formulas releasing soon · Single batch every time — every batch reformulated and matched to the latest scientific evidence · 166 evidence-based compounds across 30 products.Version 2.0 releasing soon · Single batch every time · 166 compounds across 30 products.
NEX-GEN™
Build your stack

Formulas built the way I would build them for myself.

Tier 3 · mechanistic / traditional / early human

Black ginger extract (Kaempferia parviflora, 5% methoxyflavones)

Small RCTs (100–150 mg/day): improved physical fitness/grip in older adults, hand-grip and NO markers; AMPK/SIRT activation preclinical.

5/10evidence score
100 mgstudied dose used

What the evidence shows

Small RCTs (100–150 mg/day): improved physical fitness/grip in older adults, hand-grip and NO markers; AMPK/SIRT activation preclinical.

Tier is our appraisal of the human evidence at the dose we use: Tier 1 = multiple randomized trials; Tier 2 = human trials, fewer or smaller; Tier 3 = mechanistic, traditional or early human data; Tier 4 = emerging. Ingredients below Tier 2 are included only where the safety record is long and the traditional use is specific.

Form and dose

Form used
KPE 5% polymethoxyflavones
Dose per serving
100 mg
Delivery
Standard / as studied

Who should be careful

None significant. Talk with your clinician before starting if any of this applies to you.

In our formulas

FAQ

Which NEX-GEN formulas contain Black ginger extract (Kaempferia parviflora, 5% methoxyflavones)?

Ultimate Longevity (100 mg per serving). Every formula lists its full dose on the Supplement Facts panel — no proprietary blends.

What form of Black ginger extract does NEX-GEN use and why?

KPE 5% polymethoxyflavones. We choose the most bioavailable form we can source at the studied dose.

What does the evidence actually show for Black ginger extract?

Small RCTs (100–150 mg/day): improved physical fitness/grip in older adults, hand-grip and NO markers; AMPK/SIRT activation preclinical.

Who should be careful with it?

None significant. Talk with your clinician before starting if any of this applies to you.

Sources

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition. Last reviewed October 2026.

The Ultimate Handbook of Health — cover
The protocols we cannot publish here

Book a “What I Would Do If I Were You” consultation

A one-hour, one-on-one session with Jason Johns that ends with your own customized edition of The Ultimate Handbook of Health: detailed, personalized protocols including peptides, bioregulators, and highly specific supplement timing and an interactions checker — a stack designed for your biology and taken when it can actually be absorbed.

  • Full review of your goals, labs and current stack
  • Customized Handbook (Version 2.0 — now with infographics) written for you
  • Sourcing guidance and what to track at each follow-up