Version 2.0 formulas releasing soon · Single batch every time — every batch reformulated and matched to the latest scientific evidence · 166 evidence-based compounds across 30 products.Version 2.0 releasing soon · Single batch every time · 166 compounds across 30 products.
Formulas built the way I would build them for myself.
Tier 1 · multiple human RCTs
Pycnogenol® French maritime pine bark extract
Randomized double-blind crossover (Enseleit, Eur Heart J): improved endothelial function in CAD patients at 200 mg; 100 mg/day improved FMD in healthy adults; >160 trials.
9/10evidence score
Horphag Researchlicensed form owner
100 mgstudied dose used
What the evidence shows
Randomized double-blind crossover (Enseleit, Eur Heart J): improved endothelial function in CAD patients at 200 mg; 100 mg/day improved FMD in healthy adults; >160 trials.
Tier is our appraisal of the human evidence at the dose we use: Tier 1 = multiple randomized trials; Tier 2 = human trials, fewer or smaller; Tier 3 = mechanistic, traditional or early human data; Tier 4 = emerging. Ingredients below Tier 2 are included only where the safety record is long and the traditional use is specific.
Form and dose
Form used
65–75% procyanidins
Branded source
Horphag Research
Dose per serving
100 mg
Delivery
Standard / as studied
Who should be careful
Mild GI; theoretical additive with antiplatelets. Talk with your clinician before starting if any of this applies to you.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition. Last reviewed October 2026.
The protocols we cannot publish here
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