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Tier 2 · human trials, fewer or smaller

OXYSTORM® red spinach extract (9% nitrate)

RCT (n=16): 2 g raised plasma/salivary nitrate-nitrite; 1 g raised calf blood flow at 30 min and delayed ventilatory threshold; 7–15-day intake improved 4-km TT and time-to-exhaustion (~19%).

7/10evidence score
N.C.T. Corporation / Barlowe'slicensed form owner
1000 mgstudied dose used

What the evidence shows

RCT (n=16): 2 g raised plasma/salivary nitrate-nitrite; 1 g raised calf blood flow at 30 min and delayed ventilatory threshold; 7–15-day intake improved 4-km TT and time-to-exhaustion (~19%).

Tier is our appraisal of the human evidence at the dose we use: Tier 1 = multiple randomized trials; Tier 2 = human trials, fewer or smaller; Tier 3 = mechanistic, traditional or early human data; Tier 4 = emerging. Ingredients below Tier 2 are included only where the safety record is long and the traditional use is specific.

Form and dose

Form used
Amaranthus dubius leaf extract, 9% nitrate, oxalate-free
Branded source
N.C.T. Corporation / Barlowe's
Dose per serving
1000 mg
Delivery
Standard / as studied

Who should be careful

Avoid with PDE-5 inhibitors or nitrate drugs (additive hypotension); mouthwash blunts conversion. Talk with your clinician before starting if any of this applies to you.

In our formulas

FAQ

Which NEX-GEN formulas contain OXYSTORM® red spinach extract (9% nitrate)?

Ultimate Blood Flow (250 mg per serving) · Ultimate Pre-Workout (1,000 mg per serving) · Forever Young (500 mg per serving). Every formula lists its full dose on the Supplement Facts panel — no proprietary blends.

What form of OXYSTORM® red spinach extract does NEX-GEN use and why?

Amaranthus dubius leaf extract, 9% nitrate, oxalate-free. We use the licensed branded form so the dose on our label matches the material studied in the trials.

What does the evidence actually show for OXYSTORM® red spinach extract?

RCT (n=16): 2 g raised plasma/salivary nitrate-nitrite; 1 g raised calf blood flow at 30 min and delayed ventilatory threshold; 7–15-day intake improved 4-km TT and time-to-exhaustion (~19%).

Who should be careful with it?

Avoid with PDE-5 inhibitors or nitrate drugs (additive hypotension); mouthwash blunts conversion. Talk with your clinician before starting if any of this applies to you.

Sources

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition. Last reviewed October 2026.

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