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Tier 2 · human trials, fewer or smaller

Akkermansia muciniphila WB-STR-001 (pasteurized)

RCT (n=32): pasteurized A. muciniphila 10^10/day × 3 mo improved insulin sensitivity and liver enzymes (Depommier 2019); Amansia weight trial.

7/10evidence score
Pendulumlicensed form owner
0.1 B AFUstudied dose used

What the evidence shows

RCT (n=32): pasteurized A. muciniphila 10^10/day × 3 mo improved insulin sensitivity and liver enzymes (Depommier 2019); Amansia weight trial.

Tier is our appraisal of the human evidence at the dose we use: Tier 1 = multiple randomized trials; Tier 2 = human trials, fewer or smaller; Tier 3 = mechanistic, traditional or early human data; Tier 4 = emerging. Ingredients below Tier 2 are included only where the safety record is long and the traditional use is specific.

Form and dose

Form used
100 M AFU
Branded source
Pendulum
Dose per serving
0.1 B AFU
Delivery
Standard / as studied

Who should be careful

None significant. Talk with your clinician before starting if any of this applies to you.

In our formulas

FAQ

Which NEX-GEN formulas contain Akkermansia muciniphila WB-STR-001 (pasteurized)?

Gut Biome (100 million AFU per serving). Every formula lists its full dose on the Supplement Facts panel — no proprietary blends.

What form of Akkermansia muciniphila WB-STR-001 does NEX-GEN use and why?

100 M AFU. We use the licensed branded form so the dose on our label matches the material studied in the trials.

What does the evidence actually show for Akkermansia muciniphila WB-STR-001?

RCT (n=32): pasteurized A. muciniphila 10^10/day × 3 mo improved insulin sensitivity and liver enzymes (Depommier 2019); Amansia weight trial.

Who should be careful with it?

None significant. Talk with your clinician before starting if any of this applies to you.

Sources

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition. Last reviewed October 2026.

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