Version 2.0 formulas releasing soon · Single batch every time — every batch reformulated and matched to the latest scientific evidence · 166 evidence-based compounds across 30 products.Version 2.0 releasing soon · Single batch every time · 166 compounds across 30 products.
Jason's rotating probiotic layer in one delayed-release capsule pair: Bacillus spores, pasteurized Akkermansia, PS128™, L. reuteri DSM 17938, LGG®, B. longum 1714™, a postbiotic and 200 mg HMO.
Supports a diverse, resilient gut microbiome*
Supports gut-brain axis balance, mood and stress resilience*
Supports healthy metabolic and immune function*
Choose how to buy
$149$127/mo on subscription · from $112/unit on a 3-pack subscription
No payment is collected today — pre-orders are saved to your list and confirmed by email. Checkout opens January 1, 2027. How pricing works.
Serving
2 capsules
Servings
30
Format
Capsule · size 0 (DR)
Timing
Empty stomach, AM
Contents
60 capsules · 30 servings
Why these ingredients
Every ingredient, every dose, and the evidence behind it
No proprietary blends. Each line below is on the Supplement Facts panel at exactly this amount. Tier is our appraisal of the human evidence; sources are linked.
Directions: Take 2 capsules on an empty stomach in the morning. Rotate 8 weeks on / 2 weeks off.
*Formulations are unofficial — Version 2.0 specifications are being finalized ahead of the first single-batch run and may change before release. Supplement Facts shown are the current design targets, not a finished label.
Label preview
Wrap-around label, unfolded — front panel + Supplement FactsKey branded ingredients at the studied doseFront · back
Matte black label on amber glass with metallic blue edges. Final artwork is proofed before the first run.
Who should not take this. Immunocompromised individuals: consult physician before use. Talk with your clinician before starting if you take medication, are pregnant or nursing, or have a medical condition.
Price ladder
One-time
$149
Subscribe monthly
$127
3-pack
$119/unit
3-pack subscription
$112/unit
Stack it with up to four other formulas for 5–25% more off every rung. Build a stack →
NexGen Outcomes Program
Buy a 3-pack (one-time or subscription), complete four short surveys over 90 days, and earn back 25% of what you paid as store credit — or 40% as subscription credit. Self-reported, published in aggregate, never called a clinical trial.
Version 2.0 is made once. When this batch sells out it is gone; the next version is announced before it is made. If this formula is working for you, tell us to keep it — and buy a few extra bottles just in case.
The Depommier RCT that improved insulin sensitivity used the pasteurized form, which is also shelf-stable in a capsule.
What does "Version 2.0" mean?
Every NEX-GEN formula starts at Version 2.0 and later versions may be announced each quarter. Each run is a single batch — once it sells out, that exact version is retired. If you love a version, tell us to keep it, and buy a few extra bottles just in case.
How does pre-order work?
Pre-order adds the item to your saved cart and emails a confirmation that your bottles are reserved. No payment is taken now; you will be prompted to complete checkout when the Version 2.0 batch releases in early 2027.
When does it ship?
Version 2.0 ships early 2027 in the order pre-orders were placed. Pre-orders open January 1, 2027; until then you can save it to your list at no cost.
Changelog
Version history
Version 2.0
Initial release · batch 1. First formula we would put our name on: 8 actives at full studied doses, capsule format, 60 capsules · 30 servings.
Version 2.1 candidates
v2.1 candidates: add B. infantis 35624 if license obtained. Candidates are listed before any batch is made — tell us what to keep.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition.
$99$84/mo on subscription · from $74/unit on a 3-pack subscription
The protocols we cannot publish here
Book a “What I Would Do If I Were You” consultation
A one-hour, one-on-one session with Jason Johns that ends with your own customized edition of The Ultimate Handbook of Health: detailed, personalized protocols including peptides, bioregulators, and highly specific supplement timing and an interactions checker — a stack designed for your biology and taken when it can actually be absorbed.
Full review of your goals, labs and current stack
Customized Handbook (Version 2.0 — now with infographics) written for you
Sourcing guidance and what to track at each follow-up
