Small moleculeVersion 2.0 · Single batch

AMPK Activator · ATX-304

Version 2.0Single-batch runChangelog

Pan-AMPK activator · 100 mg · cycled

100 mg of ATX-304 (OS-01) per capsule — the oral pan-AMPK activator Jason cycles 8–12 weeks at a time, in a single-compound capsule so the dose is yours to titrate.

Supports healthy AMPK signaling and cellular energy metabolism*
Supports healthy fat oxidation and metabolic function already within the normal range*
Supports mitochondrial energy production*

Choose how to buy

~~$199~~ $169/mo on subscription · from $149/unit on a 3-pack subscription

Subscribe monthly save 15%~~$199~~ $169One unit every 30 days · free shipping · skip, swap or cancel any time One-time$199Anchor price · single unit 3-pack save 20%~~$597~~ $477 ($159/unit)90-day supply, shipped once · Outcomes Program eligible 3-pack subscription save 25%~~$597~~ $447 ($149/unit)Three units every 90 days · best per-unit price · Outcomes Program eligible

Add to a stack · up to 25% more off

No payment is collected today — pre-orders are saved to your list and confirmed by email. Checkout opens January 1, 2027. How pricing works.

Serving: 1 capsule
Servings: 60
Format: Capsule · size 1
Timing: Morning, empty stomach
Contents: 60 capsules · 60 servings

Why these ingredients

Every ingredient, every dose, and the evidence behind it

No proprietary blends. Each line below is on the Supplement Facts panel at exactly this amount. Tier is our appraisal of the human evidence; sources are linked.

ATX-304 (OS-01 · O-304 sodium salt, pan-AMPK activator)

100 mg

Micronized O-304 sodium salt ≥98% (HPLC), enteric-protectedTier 3

Evidence. Phase 2a RCT (n=65, T2D on metformin, 1,000 mg/day × 28 d): improved glucose handling, blood pressure and 6-min walk distance; 2026 phase 1b (n=23, obesity/prediabetes, 400 mg/day × 8 wk): lower liver and visceral fat, higher resting energy expenditure. Consumer capsules standardize to 100 mg; typical use 100–300 mg/day in 8–12 week cycles.

Cautions. Investigational compound — no long-term human safety data; may add to glucose-lowering medication (monitor); cycle 8–12 weeks on / equal time off; not in pregnancy or nursing.

pubmed.ncbi.nlm.nih.gov/?term=O304+AMPK+a…peptidelibrary.app/library/atx-304 biolongevitysupplements.com/product/bioamp/

Supplement Facts

Serving size 1 capsule
Servings per container 60

	Amount per serving	% DV
ATX-304 (OS-01 · O-304 sodium salt, pan-AMPK activator)	100 mg	†

† Daily Value not established. Percent Daily Values are based on a 2,000-calorie diet.

Other ingredients: acid-resistant plant-based capsule (DRcaps®), microcrystalline cellulose, sunflower lecithin.

Directions: Take 1 capsule in the morning on an empty stomach. After one week, a second capsule in the early afternoon may be added (up to 3 per day). Run 8–12 weeks, then rest an equal period.

*Formulations are unofficial — Version 2.0 specifications are being finalized ahead of the first single-batch run and may change before release. Supplement Facts shown are the current design targets, not a finished label.

Label preview

AMPK Activator · ATX-304 wrap-around label, unfolded: front panel and Supplement Facts — Wrap-around label, unfolded — front panel + Supplement Facts

AMPK Activator · ATX-304 key branded ingredients card — Key branded ingredients at the studied dose

AMPK Activator · ATX-304 bottle, front — Front · back

AMPK Activator · ATX-304 bottle, back — Supplement Facts — Front · back

Matte black label on amber glass with metallic blue edges. Final artwork is proofed before the first run.

Who should not take this. Not for use with glucose-lowering medication without physician supervision; not in pregnancy or nursing; not under 18. Investigational-class compound — see the product FAQ. Talk with your clinician before starting if you take medication, are pregnant or nursing, or have a medical condition.

Price ladder

One-time	~~$199~~
Subscribe monthly	$169
3-pack	$159/unit
3-pack subscription	$149/unit

Stack it with up to four other formulas for 5–25% more off every rung. Build a stack →

NexGen Outcomes Program

Buy a 3-pack (one-time or subscription), complete four short surveys over 90 days, and earn back 25% of what you paid as store credit — or 40% as subscription credit. Self-reported, published in aggregate, never called a clinical trial.

How it works

Single-batch promise

Version 2.0 is made once. When this batch sells out it is gone; the next version is announced before it is made. If this formula is working for you, tell us to keep it — and buy a few extra bottles just in case.

Read the changelog

FAQ

Questions about AMPK Activator · ATX-304

What is ATX-304 (OS-01)?

A small-molecule, direct pan-AMPK activator (also called O-304). AMPK is the cellular energy sensor exercise and fasting switch on. Two small placebo-controlled human trials (1,000 mg/day × 28 days; 400 mg/day × 8 weeks) have been published; it is still an investigational compound, which is why we sell it alone, at a conservative 100 mg capsule, and ask you to cycle it.

Why is it a separate bottle instead of inside Ultimate Longevity?

Three reasons: it is cycled (8–12 weeks on, equal time off) while Longevity is daily; the dose is titrated 1–3 capsules; and we want you to be able to run it with or without the rest of the stack.

What does "Version 2.0" mean?

Every NEX-GEN formula starts at Version 2.0 and later versions may be announced each quarter. Each run is a single batch — once it sells out, that exact version is retired. If you love a version, tell us to keep it, and buy a few extra bottles just in case.

How does pre-order work?

Pre-order adds the item to your saved cart and emails a confirmation that your bottles are reserved. No payment is taken now; you will be prompted to complete checkout when the Version 2.0 batch releases in early 2027.

When does it ship?

Version 2.0 ships early 2027 in the order pre-orders were placed. Pre-orders open January 1, 2027; until then you can save it to your list at no cost.

Changelog

Version history

Version 2.0
Initial release · batch 1. First formula we would put our name on: 1 active at full studied doses, capsule format, 60 capsules · 60 servings.
Version 2.1 candidates
v2.1 candidates: 200 mg capsule; combined ATX-304 + 5-Amino-1MQ capsule. Candidates are listed before any batch is made — tell us what to keep.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition.

Pairs well with

The protocols we cannot publish here

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Customized Handbook (Version 2.0 — now with infographics) written for you
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AMPK Activator · ATX-304

Every ingredient, every dose, and the evidence behind it

ATX-304 (OS-01 · O-304 sodium salt, pan-AMPK activator)

Supplement Facts

Questions about AMPK Activator · ATX-304

Version history

NNMT · 5-Amino-1MQ

Ultimate Morning

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