Version 2.0 formulas releasing soon · Single batch every time — every batch reformulated and matched to the latest scientific evidence · 166 evidence-based compounds across 30 products.Version 2.0 releasing soon · Single batch every time · 166 compounds across 30 products.
Phase 2a RCT (n=65, T2D on metformin, 1,000 mg/day × 28 d): improved glucose handling, blood pressure and 6-min walk distance; 2026 phase 1b (n=23, obesity/prediabetes, 400 mg/day × 8 wk): lower liver and visceral fat, higher resting energy expenditure. Consumer capsules standardize to 100 mg; typical use 100–300 mg/day in 8–12 week cycles.
5/10evidence score
Betagenon / white-label APIlicensed form owner
100 mgstudied dose used
What the evidence shows
Phase 2a RCT (n=65, T2D on metformin, 1,000 mg/day × 28 d): improved glucose handling, blood pressure and 6-min walk distance; 2026 phase 1b (n=23, obesity/prediabetes, 400 mg/day × 8 wk): lower liver and visceral fat, higher resting energy expenditure. Consumer capsules standardize to 100 mg; typical use 100–300 mg/day in 8–12 week cycles.
Tier is our appraisal of the human evidence at the dose we use: Tier 1 = multiple randomized trials; Tier 2 = human trials, fewer or smaller; Tier 3 = mechanistic, traditional or early human data; Tier 4 = emerging. Ingredients below Tier 2 are included only where the safety record is long and the traditional use is specific.
Form and dose
Form used
Micronized O-304 sodium salt ≥98% (HPLC), enteric-protected
Branded source
Betagenon / white-label API
Dose per serving
100 mg
Delivery
Standard / as studied
Who should be careful
Investigational compound — no long-term human safety data; may add to glucose-lowering medication (monitor); cycle 8–12 weeks on / equal time off; not in pregnancy or nursing. Talk with your clinician before starting if any of this applies to you.
AMPK Activator · ATX-304 (100 mg per serving). Every formula lists its full dose on the Supplement Facts panel — no proprietary blends.
What form of ATX-304 does NEX-GEN use and why?
Micronized O-304 sodium salt ≥98% (HPLC), enteric-protected. We use the licensed branded form so the dose on our label matches the material studied in the trials.
What does the evidence actually show for ATX-304?
Phase 2a RCT (n=65, T2D on metformin, 1,000 mg/day × 28 d): improved glucose handling, blood pressure and 6-min walk distance; 2026 phase 1b (n=23, obesity/prediabetes, 400 mg/day × 8 wk): lower liver and visceral fat, higher resting energy expenditure. Consumer capsules standardize to 100 mg; typical use 100–300 mg/day in 8–12 week cycles.
Who should be careful with it?
Investigational compound — no long-term human safety data; may add to glucose-lowering medication (monitor); cycle 8–12 weeks on / equal time off; not in pregnancy or nursing. Talk with your clinician before starting if any of this applies to you.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition. Last reviewed October 2026.
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