Switch ingredient Choose… Betaine anhydrous (TMG) Choline (as choline bitartrate) CocoaVia® cocoa flavanol extract (Cocoapro™ process, 500 mg flavanols) D-ribose Ionic trace minerals (ConcenTrace®, 72 minerals) Liposomal vitamin C (PureWay-C® liposomal) Methylated B-complex (B1 benfotiamine 50 mg, B2 R5P 10 mg, B3 niacinamide 30 mg, B5 50 mg, B6 P5P 15 mg, biotin 300 mcg, folate Quatrefolic® 400 mcg DFE, B12 methyl/adenosyl 500 mcg) Molecular hydrogen tablet (magnesium-based, 8 ppm) Taurine AstaPure® natural astaxanthin (Haematococcus) Lutein + zeaxanthin (Lutemax 2020®) LYSOVETA® LPC-bound omega-3 (EPA/DHA) Saffron extract (affron®, 3.5% Lepticrosalides®) Vitamin A (as retinyl palmitate) Vitamin D3 (cholecalciferol, lichen-derived) Vitamin K1 (phytonadione) Vitamin K2 as MK-4 Vitamin K2 as MK-7 (MenaQ7®) Aquamin® Mg seawater magnesium hydroxide Boron (as boron glycinate) Chromium (as chromium picolinate) Copper (as copper bisglycinate) Humic/fulvic mineral complex (BioActive Carbon®) 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(5-amino-1-methylquinolinium) ATX-304 (OS-01 · O-304 sodium salt, pan-AMPK activator) Black ginger extract (Kaempferia parviflora, 5% methoxyflavones) Calcium alpha-ketoglutarate (delayed-release) Cyanidin-3-glucoside (black rice / bilberry, 25% C3G) Fisetin (≥98%, liposomal) GeneIII® L-ergothioneine (99.99%) Mitopure® urolithin A pTeroPure® pterostilbene Quercefit® quercetin Phytosome™ Spermidine-rich wheat germ extract (CelVio Complex®, 0.15% spermidine) Telos95® (grapevine + olive leaf polyphenols) β-NMN (nicotinamide mononucleotide), NDIN-acknowledged source 7,8-dihydroxyflavone (liposomal) AlphaSize® alpha-GPC Bacognize® Bacopa monnieri Cognizin® citicoline enfinity® paraxanthine kollaJell™ hydrolyzed jellyfish collagen Lion's mane (Hericium erinaceus) fruiting body + mycelium 8:1, erinacine-A standardized Magtein® magnesium L-threonate Mucuna pruriens seed extract (15% L-DOPA) N-acetyl-L-tyrosine Rhodiolife® Rhodiola rosea (3% rosavins, 1% salidroside) Sharp-PS® GREEN sunflower phosphatidylserine Vitamin B6 (pyridoxal-5′-phosphate) Apigenin (liposomal, ≥98%) Bifidobacterium longum 1714™ (ZenBiome™ strain) Chamomile flower extract (1.2% apigenin) Glycine Honokiol (liposomal, 98% from Magnolia officinalis) Lactium® (αS1-casein hydrolysate, α-casozepine) Levagen®+ palmitoylethanolamide (LipiSperse®) Magnesium bisglycinate chelate (TRAACS®) Suntheanine® L-theanine Akkermansia muciniphila WB-STR-001 (pasteurized) Aloe vera inner leaf 200:1 (acemannan ≥10%) Bacillus subtilis HU58™ + B. coagulans (spore blend) BPC-157 arginine salt (oral-stable) CoreBiome® tributyrin DGL licorice (deglycyrrhizinated, 4:1) KPV tripeptide (Lys-Pro-Val) L-glutamine Lacticaseibacillus rhamnosus GG (LGG®) Lactiplantibacillus plantarum PS128™ Larazotide acetate (octapeptide) Limosilactobacillus reuteri DSM 17938 Sodium bicarbonate (buffer) Zinc L-carnosine (PepZin GI®) 2′-fucosyllactose + LNnT human-milk oligosaccharides (SuperHMO®) Acacia (gum arabic) fiber DigeZyme® multi-enzyme complex Ginger root extract (5% gingerols) Heat-killed Lactobacillus/Bifidobacterium postbiotic blend (e.g., L. paracasei MCC1849) ImmunoLin® serum bovine immunoglobulin Liposomal bovine colostrum (30% IgG) Sunfiber® partially hydrolyzed guar gum Acetyl-L-carnitine Calcium D-glucarate Gamma-glutamylcysteine (GGC) Milk thistle (Siliphos® silybin phytosome) N-acetyl-L-cysteine (NAC) N-acetyl-L-cysteine ethyl ester (NACET) Olive leaf extract (20% oleuropein + hydroxytyrosol) Phosphatidylcholine (sunflower, ≥50%) Setria® L-glutathione (reduced) Stabilized R-lipoic acid (Na-R-ALA) Stabilized sulforaphane complex (broccoli seed glucoraphanin + active myrosinase) TUDCA (tauroursodeoxycholic acid) 6′-sialyllactose (6′-SL) HMO Cluster Dextrin® highly branched cyclic dextrin Creapure® creatine monohydrate Creatine hydrochloride Electrolyte complex (sodium 300 mg, potassium 200 mg, magnesium 50 mg from Aquamin® Mg, chloride) Essential amino acids (fermentation, leucine-enriched 40%) Grass-fed whey protein isolate (cold-processed, non-denatured) Guanidinoacetic acid (GAA) L-citrulline (fermentation) L-ornithine α-ketoglutarate (OKG) LactoSpore® Bacillus coagulans MTCC 5856 Mediator® phosphatidic acid (soy, 50%) PeakATP® (adenosine 5′-triphosphate disodium) PeptiStrong® fava bean protein hydrolysate ProHydrolase® protease blend FORTIBONE® bioactive collagen peptides FORTIGEL® bioactive collagen peptides Hyaluronic acid (HyaCera™, low molecular weight) TENDOFORTE® bioactive collagen peptides UC-II® undenatured type II collagen VERISOL® bioactive collagen peptides Catuaba bark 10:1 extract (Barlowe's) Cistanche deserticola 10:1 extract (Barlowe's) Mondia whitei tuber 5:1 extract (Barlowe's) Mpesu root powder (Securidaca longepedunculata, Barlowe's) Bonomarlot® (A-20) natural bone marrow peptide complex Cerluten® (A-5) natural brain cortex peptide complex Chelohart® (A-14) natural heart muscle peptide complex Endoluten® (A-8) natural pineal gland peptide complex Glandokort® (A-17) natural adrenal peptide complex Gotratix® (A-18) natural skeletal muscle peptide complex Libidon® (A-16) natural prostate peptide complex NexGen BioShield™ delivery matrix (sunflower phospholipid liposome + acid-resistant DRcaps®) R-alpha-lipoic acid (bioregulator cofactor) Sigumir® (A-4) natural cartilage peptide complex Svetinorm® (A-7) natural liver peptide complex Testoluten® (A-13) natural testes peptide complex Thyreogen® (A-2) natural thyroid peptide complex Ventfort® (A-3) natural blood vessel peptide complex Vladonix® (A-6) natural thymus peptide complex Zhenoluten® (A-15) natural ovary peptide complex Aged garlic extract (Kyolic®) AHCC® (Amino Up) C60 fullerene in olive oil Dihydroberberine (GlucoVantage®) Herbatonin® plant melatonin Lithium orotate (micro-dose) PectaSol® modified citrus pectin Systemic enzymes (serrapeptase + nattokinase)
On this page
Evidence Form & dose Cautions In our formulas FAQ Sources
Tier 1 · multiple human RCTs
Magnesium citrate
Highly bioavailable; multiple RCTs (BP, migraine).
9 /10 evidence score
300 mg studied dose used
What the evidence shows Highly bioavailable; multiple RCTs (BP, migraine).
Tier is our appraisal of the human evidence at the dose we use: Tier 1 = multiple randomized trials; Tier 2 = human trials, fewer or smaller; Tier 3 = mechanistic, traditional or early human data; Tier 4 = emerging. Ingredients below Tier 2 are included only where the safety record is long and the traditional use is specific.
Who should be careful Laxative at high dose. Talk with your clinician before starting if any of this applies to you.
FAQ Which NEX-GEN formulas contain Magnesium citrate? Ultimate Minerals (200 mg per serving). Every formula lists its full dose on the Supplement Facts panel — no proprietary blends.
What form of Magnesium citrate does NEX-GEN use and why? Tri-magnesium citrate (16% Mg). We choose the most bioavailable form we can source at the studied dose.
What does the evidence actually show for Magnesium citrate? Highly bioavailable; multiple RCTs (BP, migraine).
Who should be careful with it? Laxative at high dose. Talk with your clinician before starting if any of this applies to you.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition. Last reviewed October 2026.
