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Version 2.0 formulas releasing soon · Single batch every time — every batch reformulated and matched to the latest scientific evidence · 166 evidence-based compounds across 30 products.Version 2.0 releasing soon · Single batch every time · 166 compounds across 30 products.
NEX-GEN™
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Tier 1 · multiple human RCTs

UC-II® undenatured type II collagen

Multiple RCTs (40 mg/day): knee flexibility and joint comfort in healthy adults and OA (superior to glucosamine+chondroitin).

9/10evidence score
Lonzalicensed form owner
40 mgstudied dose used

What the evidence shows

Multiple RCTs (40 mg/day): knee flexibility and joint comfort in healthy adults and OA (superior to glucosamine+chondroitin).

Tier is our appraisal of the human evidence at the dose we use: Tier 1 = multiple randomized trials; Tier 2 = human trials, fewer or smaller; Tier 3 = mechanistic, traditional or early human data; Tier 4 = emerging. Ingredients below Tier 2 are included only where the safety record is long and the traditional use is specific.

Form and dose

Form used
Chicken sternal cartilage, 40 mg
Branded source
Lonza
Dose per serving
40 mg
Delivery
Standard / as studied

Who should be careful

Chicken allergen. Talk with your clinician before starting if any of this applies to you.

In our formulas

FAQ

Which NEX-GEN formulas contain UC-II® undenatured type II collagen?

Ultimate Recovery (40 mg per serving). Every formula lists its full dose on the Supplement Facts panel — no proprietary blends.

What form of UC-II® undenatured type II collagen does NEX-GEN use and why?

Chicken sternal cartilage, 40 mg. We use the licensed branded form so the dose on our label matches the material studied in the trials.

What does the evidence actually show for UC-II® undenatured type II collagen?

Multiple RCTs (40 mg/day): knee flexibility and joint comfort in healthy adults and OA (superior to glucosamine+chondroitin).

Who should be careful with it?

Chicken allergen. Talk with your clinician before starting if any of this applies to you.

Sources

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition. Last reviewed October 2026.

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