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Tier 2 · human trials, fewer or smaller

Mediator® phosphatidic acid (soy, 50%)

8-wk RCT (n=28): PA 750 mg + resistance training increased lean mass and strength vs placebo; replication mixed (H-note).

7/10evidence score
Chemi Nutralicensed form owner
750 mgstudied dose used

What the evidence shows

8-wk RCT (n=28): PA 750 mg + resistance training increased lean mass and strength vs placebo; replication mixed (H-note).

Tier is our appraisal of the human evidence at the dose we use: Tier 1 = multiple randomized trials; Tier 2 = human trials, fewer or smaller; Tier 3 = mechanistic, traditional or early human data; Tier 4 = emerging. Ingredients below Tier 2 are included only where the safety record is long and the traditional use is specific.

Form and dose

Form used
PA 750 mg studied
Branded source
Chemi Nutra
Dose per serving
750 mg
Delivery
Standard / as studied

Who should be careful

Soy allergen. Talk with your clinician before starting if any of this applies to you.

In our formulas

FAQ

Which NEX-GEN formulas contain Mediator® phosphatidic acid (soy, 50%)?

Muscle & Strength (750 mg per serving). Every formula lists its full dose on the Supplement Facts panel — no proprietary blends.

What form of Mediator® phosphatidic acid does NEX-GEN use and why?

PA 750 mg studied. We use the licensed branded form so the dose on our label matches the material studied in the trials.

What does the evidence actually show for Mediator® phosphatidic acid?

8-wk RCT (n=28): PA 750 mg + resistance training increased lean mass and strength vs placebo; replication mixed (H-note).

Who should be careful with it?

Soy allergen. Talk with your clinician before starting if any of this applies to you.

Sources

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Nothing on this site is medical advice — it is educational "what I would do if I were you" guidance from an executive health coach. Talk with your clinician before starting any supplement, especially if you take medication, are pregnant or nursing, or have a medical condition. Last reviewed October 2026.

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